I grew up in L.A., and I don't think I've seen L.A. onscreen in a way that felt real to me. There are definitely movies, but they are few and far between.
Well, in pharmacology, if the effect is local, it's of course absolutely awkward to use it in any other way than as a local treatment.
A man must be both stupid and uncharitable who believes there is no virtue or truth but on his own side.