I think a lot of the instincts you have doing comedy are really the same for doing drama, in that it's essentially about listening. The way I approach comedy, is you have to commit to everything as if it's a dramatic role, meaning you play it straight.
“Yes, hell exists. It is not a fairy tale. One indeed burns there. This hell is not at the end of life. It is here. At the beginning. Hell is what the infant must experience before he gets to us.”
“If my goal is to become a movie star, me working at a pizza shop won't help me. I have to make the stars align.”