What could be more lonely than to be enveloped in silence, to be the last of your people to speak your native tongue, to have no way to pass on the wisdom of the elders, to anticipate the promise of the children. This tragic fate is indeed the plight of someone somewhere roughly every two weeks.
I'd studied 16th century science and magic. I thought it was strange that people were interested in the same kinds of things my research was about. The more I thought about it, the more intriguing it became and pretty soon I was writing a novel about a reluctant witch and a 1500-year-old vampire.