If at first you don't succeed, try, try again. Then quit. There's no point in being a damn fool about it.
I think that if there are positions that you can't argue... then the responsibility is probably to resign. If one's own conscience is opposed to the requirements and responsibilities of the job, then it's time to leave the job.
The CIO put up half a million dollars for Roosevelt's 1936 campaign and provided him with an immense group of active labor workers who played a large part in the sweeping victory he won at the polls.