I can't think of anyone I admire who isn't fuelled by self-doubt. It's an essential ingredient. It's the grit in the oyster.
I'd love to be the first one to say this, but it automatically turns into - we all have those responsibilities that we ignore because we don't feel like they're ours.
There are MAYBE 30 years worth of ideas out there... watch for the feature version of ER in about 25 years... Hollywood has become hopelessly chained to the bottom line.