Even if I had $200 million, I'm very wary of overusing CGI. I think it's a great tool and it can be used really effectively, but I feel like it does tend to be overused and especially in sci-fi stuff.
The passage of time is a continuing thing. At 18, you're going to live forever, and you are definitely not at 52, so that is a recurring topic. I still think it's the main stuff.