You just never give up, no matter how hard the challenges are, and observe this world with a healthy dose of criticism and don't just follow the herd like somebody else might do.
Lance Armstrong, the famous cyclist and more importantly, cancer survivor, has said 'if you ever get a second chance for something, you've got to go all the way.'
If someone's criticism is completely unfounded on data, then I don't want to hear it. It doesn't hold up to scrutiny.