The greatest grand challenge for any scientist is discovering how to prevent the spread of HIV and finding the cure or an effective vaccine for AIDS.
Good management is the art of making problems so interesting and their solutions so constructive that everyone wants to get to work and deal with them.
If I'd just been interested in record sales, I would have taken one of the deals I was offered after 'Soapstar Superstar,' made a quick covers album and probably had some success for five minutes. I decided that wasn't for me.

