Perhaps more than any other disease before or since, syphilis in early modern Europe provoked the kind of widespread moral panic that AIDS revived when it struck America in the 1980s.
Going from sharing a one-bedroom place to living in a loft to two people living in a house to me having my own place by myself has kind of mirrored my career... small steps to bigger, to bigger, to now having a steady job.
A sharp tongue is the only edge tool that grows keener with constant use.