Most research into life's murky origin has been carried out by chemists. They've tried a variety of approaches in their attempts to recreate the first steps on the road to life, but little progress has been made. Perhaps that is no surprise, given life's stupendous complexity.
I was told my whole life, you're fat, you're ugly, you're never going to amount to be anything.
Another challenge? Getting up at 6:30 in the morning to go act. It's not fun acting that early in the morning or acting at 4 A.M in the middle of the night or in the morning when you're really tired. That's a challenge. What a luxurious problem to have.