A permanent base on Mars would have a number of advantages beyond being a bonanza for planetary science and geology. If, as some evidence suggests, exotic micro-organisms have arisen independently of terrestrial life, studying them could revolutionise biology, medicine and biotechnology.
If you look at some shows that have an ugly feel to them, or a nihilistic sort of feel to them, you'll usually find a group of cynical, unhappy, miserable people behind the production. If you see a show that's rather boring, or a cookie-cutter factory show, you'll usually find some pretty uninterest

