Obstacles don't have to stop you. If you run into a wall, don't turn around and give up. Figure out how to climb it, go through it, or work around it.
Unless you're flat out dead, you have to think of some other questions like: what's on the other side? It brings up issues of God, or no God. How does he play into this? Or he, or she, or it? How does it all play into this?
I'm old enough to have friends and contemporaries who have long since retired, and that's their prerogative - enough is enough; it doesn't mean a thing to me. But I haven't got any money, so, you know, I just keep on working.