If you're trying to achieve, there will be roadblocks. I've had them; everybody has had them. But obstacles don't have to stop you. If you run into a wall, don't turn around and give up. Figure out how to climb it, go through it, or work around it.
It's like you asked me about the depression thing: you grope towards an understanding of whatever it is your going through, and it's not personal, there are forces in play around you, and you seek to understand them and that way you can go on.