Most entrepreneurs are merely technicians with an entrepreneurial seizure. Most entrepreneurs fail because you are working IN your business rather than ON your business.
I think there is an element of nihilism about, but I don't think most artists feel their work is meaningless.
We found out the Gemini spacesuit was, well, oxygen was flowing to keep me cool as well as to breathe, and it wasn't good enough. My visor got fogged.

