For me, the great joy is to watch an audience watching what I've made. To hear not a peep from the audience at the right moment, and then to hear the laughs and the cheers.
We know that appropriators will fight these cutbacks. But by eliminating earmarks, we can stop the horse trading that grows agency budgets.
What does gene A do? What does gene B do? What does it do in different contexts? What's its importance? We know the answer to that for a very small number of genes, the ones that made themselves evident many years ago.

