As far as a truly radical conscience, you have to take it as part of a larger thing, that it was sort of historical inevitability that with the coming of a leaguer society people would start to use drugs a lot more then they had before.
It's generally much easier to kill an organization than to change it substantially.
There's a practical problem about time and energy, and a more subtle problem of what it does to a writer's head, to continually analyze why they write, where it all comes from, where it's going to.