It's a little like casting out hundreds of fishing lines into the audience. You start getting little bites, then more, then you hook a few, then more. Then you can start reeling them in and that's a loveliest feeling - the whole audience laughing with you.
I never know how to give advice to a writer because there's so much you could say, and it's hard to translate your own experience. But of course, I always try. The main thing that I usually end up saying is to read a lot. To read a great deal and to learn from that.
I believe the biggest themes of life are put into the best focus when held up against the very sharp light of mortality.