I guess you can stay sort of true to the story; you don't have to artificially bring the character back from whatever doom you've designed for them, you can tell the story, I suppose, honestly.
A permanent base on Mars would have a number of advantages beyond being a bonanza for planetary science and geology. If, as some evidence suggests, exotic micro-organisms have arisen independently of terrestrial life, studying them could revolutionise biology, medicine and biotechnology.

