I can't really put it in one sentence because although on one hand Preacher is about faith and yes it is also about, I suppose, the search for God, the search for faith and the manipulation and the abuse committed by figures in whom I suppose people have faith.
A weed is a plant that has mastered every survival skill except for learning how to grow in rows.
With my somewhat vague aspiring mind, to be imprisoned in the rude details of a most material life was often irksome.