With the people, for the people, by the people. I crack up when I hear it; I say, with the handful, for the handful, by the handful, cause that's what really happens.
It does not seem, however, that organic chemists were much worried about barriers to rotation in organic molecules in general at that time because there was no technique available to demonstrate the phenomenon experimentally.
Melancholy and sadness are the start of doubt... doubt is the beginning of despair; despair is the cruel beginning of the differing degrees of wickedness.