A major one which no one can overlook is technological and based on inventions and discoveries which have altered the whole basis of production and deeply affected social relations.
Before I do anything, I think, well what hasn't been seen. Sometimes, that turns out to be something ghastly and not fit for society. And sometimes that inspiration becomes something that's really worthwhile.
One likes to think one grows as a writer as one ages, else all you get is an 'old' young writer. Beyond that is the changing landscape of the universe and the stories I choose to tell.

