What does gene A do? What does gene B do? What does it do in different contexts? What's its importance? We know the answer to that for a very small number of genes, the ones that made themselves evident many years ago.
Simplicity is not the absence of clutter, that's a consequence of simplicity. Simplicity is somehow essentially describing the purpose and place of an object and product. The absence of clutter is just a clutter-free product. That's not simple.

