Going from sharing a one-bedroom place to living in a loft to two people living in a house to me having my own place by myself has kind of mirrored my career... small steps to bigger, to bigger, to now having a steady job.
Well, in pharmacology, if the effect is local, it's of course absolutely awkward to use it in any other way than as a local treatment.
The opera is like a husband with a foreign title - expensive to support, hard to understand and therefore a supreme social challenge.

