If you believe in what you are doing, then let nothing hold you up in your work. Much of the best work of the world has been done against seeming impossibilities. The thing is to get the work done.
The name of my condition is Cartilage Hair Syndrome Hypoplasia, but you can just call me Billy.
I found out about reviews early on. They're mostly written by sad men on bad afternoons. That's probably why I'm less angry than some writers, who are so narcissistic they consider every line of every review, even a thoughtful one, as major treason.