I don't believe in pessimism. If something doesn't come up the way you want, forge ahead. If you think it's going to rain, it will.
Going from sharing a one-bedroom place to living in a loft to two people living in a house to me having my own place by myself has kind of mirrored my career... small steps to bigger, to bigger, to now having a steady job.
The Department of Cell Biology at Johns Hopkins was founded and directed by Tom Pollard, an engaging young scientist with remarkable energy and enthusiasm.