Starting out, I bet I didn't get a lot of parts because of my strange voice. I'm not consciously thinking, 'Hey, sound like a squeaky dog toy mixed with a bagful of rusty nails.' It's just what my voice has done.
As a comic, I've heard gunshots while I'm trying to get to sleep. I've performed where people wanted to do you harm after the show because of something you said.
You can maybe be artistic and really original and creative, but as long as it's got that funniness at the root of it, then certain people are going to love it just because they need a laugh.