I'm not a big fan of CGI. I'm not a fan at all, unless they use it in a way that doesn't call attention to itself.
Genes are not simple triggers. No one is hardwired to commit murder or any other crime. Our actions are always the result of stupendously complex gene-environment interactions, and environment is likely to remain the more important influence by far.
As long as I'm still able to have a hit on the radio and sell a few albums and some tickets, I don't see that it would be worth retiring.