I had two family members involved in World War I: two great-uncles. One of them is on a memorial in France. And the other was a trench runner who survived the war. The average life span of a trench runner was 36 hours, but he survived the whole war.
We humans are an extremely important manifestation of the replication bomb, because it is through us - through our brains, our symbolic culture and our technology - that the explosion may proceed to the next stage and reverberate through deep space.