I don't begin a novel or a screenplay until I know the ending. And I don't mean only that I have to know what happens. I mean that I have to hear the actual sentences. I have to know what atmosphere the words convey.
I'm at peace with my family, my friends, myself and God so there's really nothing else that I worry about.
Physical activity can get you going when you are immobilized. Get action in your life, and don't just talk about it. Get into the arena!